Our department, with Cisca Wijmenga and David van Heel as lead scientists have performed the largest genetic screen for coeliac disease, including roughly 14,000 coeliac patients and 14,000 non-coeliacs. Most, if not all our knowledge about the role of genetics in coeliac disease comes from this work. We are now in the process of expanding on this by trying to understand the processes on which the genetics associated with coeliac disease have effects. We are using large datasets with RNAseq from blood and cohorts of both the general population and coeliac disease patients. For more details on the role of genetics in coeliac disease, you can have a look at our review published in Trends in Genetics in 2016.