FAQ

I've had coeliac disease since I was 6 years old - could the research looking at causal genes explain why I developed coeliac disease as a child but others developed it when they are adults?

Very good question, and definitely something we would also like to know. We do think that there may be a link between the age of getting coeliac disease and the genetic risk an individual has. For example, children with 2HLA-DQ2 genes have a higher risk, and are often diagnosed earlier in life than children with just one HLA-DQ2 or HLA-DQ8. However, it is unclear if other genes may be important for age of onset. Also, many other factors that are not in our genes may also affect when someone could get coeliac disease, so even when a person has a relatively high risk for coeliac disease based on their genetics, they still may not get the disease, early or later in life.

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